-transparent.png){kind=logo}
Graded doses of sodium nitrite were administered shortly before or immediately after a single training trial in an inhibitory avoidance task. A retention test was given at 24 h (rats) or 72 h (mice) after training. The results indicate that sodium nitrite impairs acquisition of an inhibitory avoidance response in rats and mice. Retention was impaired with doses lower than those required for producing hypoxic effects, as measured by the EEG, methemoglobin levels in the blood, blood pressure, and heart rate. Since hypoxia was not involved, it is likely that the effects were mediated by some direct action of sodium nitrite on the CNS.
Related Publications
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
October 1986,
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
January 1975,
Acta biologica et medica Germanica,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
September 2012,
Anesthesiology,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
January 2019,
Toxicology reports,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
February 2021,
Environmental science and pollution research international,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
October 1994,
Carcinogenesis,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
October 1979,
Journal of the National Cancer Institute,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
February 1979,
International journal of cancer,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
August 1976,
Neuroscience letters,
J L Martinez, and
R A Jensen, and
B J Vasquez, and
J S Lacob, and
J L McGaugh, and
R E Purdy
December 1953,
The American journal of physiology,
