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Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of serum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti-HBs 77%, anti-Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti-smooth muscle 47%. Anti-perietal cell, anti-thyroid and anti-kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. The high incidence of anti-smooth muscle antibodies seems to be unrelated to liver disease.
J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
January 1968,
Bibliotheca haematologica,
J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
September 1987,
Lancet (London, England),
J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
April 2010,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
January 1987,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
January 1974,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
September 1965,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
July 1999,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
May 2003,
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J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
January 1993,
Vox sanguinis,
J Economidou, and
C Pathouli, and
S Hadziyannis, and
G Fostiropoulos, and
M Constantoulakis
October 1977,
Scandinavian journal of haematology,
