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An antibody against ruminant (goat, sheep, bovine) IgM is described which also cross-reacts with rabbit IgM. The antibody was found in the serum of a patient with adult coeliac disease and a selective IgA deficiency. This patient gave a false high Rose-Waaler rheumatoid factor titre due to the presence of the serum antibody to rabbit IgM that was capable of agglutinating rabbit antibody-sensitised erythrocytes.
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