BIOMAT Database Logo BIOMAT Database Logo

Severe asthmatic reaction during long-term treatment with disodium cromoglycate powder inhalations. 1979

J Serup

Inhalation of inert particles may in susceptible subjects with bronchial asthma result in reflex bronchoconstriction mediated through the vagal nerves. A case of severe asthmatic reaction with bronchial spasm in a 60-year-old man with intrinsic asthma after inhalation of disodium cromoglycate powder (Lomudal) during long-term treatment is reported. The mechanism is considered to be reflexogenic. Because of the variability in individual susceptibility during long-term treatment, inhalation therapy should always be given with close attention to asthmatic exacerbations.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011208 Powders Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed) Powder
D001986 Bronchial Spasm Spasmodic contraction of the smooth muscle of the bronchi. Bronchospasm,Bronchial Spasms,Bronchospasms,Spasm, Bronchial,Spasms, Bronchial
D004205 Cromolyn Sodium A chromone complex that acts by inhibiting the release of chemical mediators from sensitized MAST CELLS. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. Disodium Cromoglycate,Sodium Cromoglycate,Aarane,Bicromat Spray,Cromoglicic Acid,Cromoglycate,Cromoglycic Acid,Cromolyn,FPL-670,Intal,Lomudal,Nalcrom,Nasalcrom,Opticrom,Vicrom,Acid, Cromoglicic,Acid, Cromoglycic,Cromoglycate, Disodium,Cromoglycate, Sodium,FPL 670,FPL670
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001249 Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). Asthma, Bronchial,Bronchial Asthma,Asthmas
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

J Serup
[Disodium cromoglycate--long-term treatment in asthmatic children].
October 1978, Medizinische Klinik,
J Serup
Renal tubular function in asthmatic children on long-term disodium cromoglycate.
March 1972, Clinical allergy,
J Serup
Near-death asthmatic reaction induced by disodium cromoglycate.
December 1996, Internal medicine (Tokyo, Japan),
J Serup
Disodium cromoglycate in treatment of asthmatic children.
January 1973, Canadian family physician Medecin de famille canadien,
J Serup
Treatment of asthmatic children for six months with disodium cromoglycate: progress report from a long-term study.
December 1970, Clinical pediatrics,
J Serup
[Disodium cromoglycate in the treatment of asthmatic syndrome].
January 1974, Plucne bolesti i tuberkuloza,
J Serup
Experience with disodium cromoglycate in the treatment of asthmatic children.
June 1971, The Medical journal of Australia,
J Serup
Evaluation of disodium cromoglycate in asthmatic children.
July 1970, Annals of allergy,
J Serup
[Assessment of disodium cromoglycate in asthmatic children].
August 1971, Harefuah,
J Serup
Use of disodium cromoglycate during the course of specific desensitizing treatment in asthmatic patients.
May 1973, Acta allergologica,
Copied contents to your clipboard!