The physician and the infertile couple should be partners in the development of a treatment plan that optimally meets the couple's needs. The information about the benefits, side effects and costs of treatment is to be presented to the couple. Stimulation of the ovary has become the central component of rapidly developing assisted reproduction. The fundamental rule in ovulation induction is individual approach to each patient and close monitoring of the stimulation, because the dangers of ovarian hyperstimulation syndrome, multiple pregnancy and putative longer term risks. There is general agreement that multiple pregnancies, including twins, are still too common and must be avoided as they are the major causes of maternal and fetal morbidity. Since the advent of ICSI tens of oocytes are not necessary to achieve fertilization, and milder forms of ovarian stimulation should suffice in most IVF/ICSI cycles. Our target in infertility treatment should be the birth of healthy, singleton babies, with no health risks to their mothers.