Biomaterial Database

[Use of soluble ozone in combined treatment of pulmonary tuberculosis: lipid peroxidation and blood antioxidative defense systems]. 2000

I I Belianin, and R Iu Abdullaev

Changes in lipid peroxidation and blood antioxidative defense systems and red blood cell function were studied in 16 patients with prolonged progressive pulmonary tuberculosis in response to intravenous soluble ozone (SO) administration. There was a drastic rise in the activity of intraerythrocytic superoxide dismutase (SOD) and a reduction in intracellular malonic dialdehyde (MDA) levels. In the remaining patients, there was a decrease in the activity of SOD and an increase in intraerythrocytic MDA concentrations. Plasma catalase activity increased in all patients and MDA levels lowered. It is proposed that initial SO doses for patients with chronic pulmonary tuberculosis should be chosen on an individual basis by taking into account intraerythrocytic SOD-MDA changes due to SO initiation.

UI	MeSH Term	Description	Entries
D007275	Injections, Intravenous	Injections made into a vein for therapeutic or experimental purposes.	Intravenous Injections,Injection, Intravenous,Intravenous Injection
D007424	Intracellular Fluid	The fluid inside CELLS.	Fluid, Intracellular,Fluids, Intracellular,Intracellular Fluids
D008297	Male		Males
D008315	Malondialdehyde	The dialdehyde of malonic acid.	Malonaldehyde,Propanedial,Malonylaldehyde,Malonyldialdehyde,Sodium Malondialdehyde,Malondialdehyde, Sodium
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010083	Oxidants, Photochemical	Compounds that accept electrons in an oxidation-reduction reaction. The reaction is induced by or accelerated by exposure to electromagnetic radiation in the spectrum of visible or ultraviolet light.	Photochemical Oxidants
D010126	Ozone	The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).	Ground Level Ozone,Low Level Ozone,Tropospheric Ozone,Level Ozone, Ground,Level Ozone, Low,Ozone, Ground Level,Ozone, Low Level,Ozone, Tropospheric
D004912	Erythrocytes	Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.	Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man