Biomaterial Database

Methods to assay stress-activated protein kinases. 2000

A Cuenda

MRC Protein Phosphorylation Unit, University of Dundee, UK.

UI	MeSH Term	Description	Entries
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D048051	p38 Mitogen-Activated Protein Kinases	A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.	Mitogen-Activated Protein Kinase p38,p38 Mitogen-Activated Protein Kinase,p38 MAP Kinase,p38 MAPK,p38 Protein Kinase,p38 SAPK,MAP Kinase, p38,MAPK, p38,Mitogen Activated Protein Kinase p38,Protein Kinase, p38,p38 Mitogen Activated Protein Kinase,p38 Mitogen Activated Protein Kinases
D048054	Mitogen-Activated Protein Kinase 7	A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways.	Extracellular Signal-Regulated Kinase 5,BMK1 Kinase,Big MAP Kinase 1,ERK5 Kinase,MAPK7 Mitogen-Activated Protein Kinase,Mitogen-Activated Protein Kinase 7 Isoform 1,Mitogen-Activated Protein Kinase 7 Isoform 2,Extracellular Signal Regulated Kinase 5,Kinase, BMK1,Kinase, ERK5,MAPK7 Mitogen Activated Protein Kinase,Mitogen Activated Protein Kinase 7,Mitogen Activated Protein Kinase 7 Isoform 1,Mitogen Activated Protein Kinase 7 Isoform 2
D048055	Mitogen-Activated Protein Kinase 8	A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING.	JNK1 Kinase,MAPK8 Mitogen-Activated Protein Kinase,SAP Kinase-1,SAPK1 Mitogen-Activated Protein Kinase,Stress-Activated Protein Kinase 1,Stress-Activated Protein Kinase JNK1,Stress-Activated Protein Kinase gamma,c-jun Kinase-1,c-jun N-Terminal Kinase 1,MAPK8 Mitogen Activated Protein Kinase,Mitogen Activated Protein Kinase 8,SAP Kinase 1,SAPK1 Mitogen Activated Protein Kinase,Stress Activated Protein Kinase 1,Stress Activated Protein Kinase JNK1,Stress Activated Protein Kinase gamma,c jun Kinase 1,c jun N Terminal Kinase 1
D048291	Mitogen-Activated Protein Kinase 12	A 38-kDa mitogen-activated protein kinase found primarily in SKELETAL MUSCLE.	ERK6 Protein,Extracellular Signal-Regulated Kinase 6,MAPK12 Mitogen-Activated Protein Kinase,SAP Kinase 3,SAP Kinase-3,SAPK3,Stress-Activated Protein Kinase-3,p38gamma MAP Kinase,Extracellular Signal Regulated Kinase 6,Kinase 3, SAP,Kinase, p38gamma MAP,Kinase-3, SAP,Kinase-3, Stress-Activated Protein,MAP Kinase, p38gamma,MAPK12 Mitogen Activated Protein Kinase,Mitogen Activated Protein Kinase 12,Protein Kinase-3, Stress-Activated,Stress Activated Protein Kinase 3
D048292	Mitogen-Activated Protein Kinase 13	A 38-kDa mitogen-activated protein kinase found expressed at high levels in LUNG; KIDNEY; TESTIS; PANCREAS; and SMALL INTESTINE. It may play a role in regulating functions such as CELL DIFFERENTIATION and APOPTOSIS of EPITHELIAL CELLS.	MAPK13 Mitogen-Activated Protein Kinase,SAPK4,Stress-Activated Protein Kinase 4,p38delta,p38delta MAP Kinase,Kinase, p38delta MAP,MAP Kinase, p38delta,MAPK13 Mitogen Activated Protein Kinase,Mitogen Activated Protein Kinase 13,Stress Activated Protein Kinase 4
D020928	Mitogen-Activated Protein Kinases	A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).	Mitogen Activated Protein Kinase,Mitogen-Activated Protein Kinase,Kinase, Mitogen-Activated Protein,Kinases, Mitogen-Activated Protein,Mitogen Activated Protein Kinases,Protein Kinase, Mitogen-Activated,Protein Kinases, Mitogen-Activated