Biomaterial Database

Increased lysosomal enzyme activities in tissues of rats suffering from chlorphentermine induced lipidosis. 1979

H Lüllmann, and E U Mösinger

UI	MeSH Term	Description	Entries
D007672	Kidney Cortex	The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.	Cortex, Kidney
D008064	Lipidoses	Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved.	Lipidosis,Lipoidosis
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D008247	Lysosomes	A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed).	Autolysosome,Autolysosomes,Lysosome
D008297	Male		Males
D008361	Mannosidases	Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE.	Mannosidase
D010645	Phentermine	A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.	Adipex-P,Duromine,Ionamine,Phentermine Hydrochloride,Adipex P,AdipexP,Hydrochloride, Phentermine
D002745	Chlorphentermine	A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of DEXTROAMPHETAMINE. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)	Avipron,Chlorphentermine Hydrochloride,Desopimon,Pre-Sate,Hydrochloride, Chlorphentermine
D005966	Glucuronidase		Endo-beta-D-Glucuronidase,Endoglucuronidase,Exo-beta-D-Glucuronidase,beta-Glucuronidase,Endo beta D Glucuronidase,Exo beta D Glucuronidase,beta Glucuronidase
D000135	Acid Phosphatase	An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.	Acid beta-Glycerophosphatase,Acid beta Glycerophosphatase

Related Publications

H Lüllmann, and E U Mösinger

Experimental chlorphentermine lipidosis of the retina in albino rats.

January 1993, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde,

H Lüllmann, and E U Mösinger

Lipidosis-like cellular alterations in lymphatic tissues of chlorphentermine-treated animals.

January 1974, Virchows Archiv. B, Cell pathology,

H Lüllmann, and E U Mösinger

Changes in lysosomal enzyme activities of eye tissues in endotoxin-induced inflammation.

September 1983, Inflammation,

H Lüllmann, and E U Mösinger

[Chlorphentermine-induced lipidosis of the cochlea and the cochlear nucleus].

November 1983, Laryngologie, Rhinologie, Otologie,

H Lüllmann, and E U Mösinger

Cerulein-induced pancreatitis in rats: increased lysosomal enzyme activity and autophagocytosis.

January 1985, Digestion,

H Lüllmann, and E U Mösinger

Amiodarone-induced lipidosis-like alterations in ocular tissues of rats.

July 1978, Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,

H Lüllmann, and E U Mösinger

Lysosomal enzyme activities in ocular tissues and adnexa of rabbits.

January 1989, Ophthalmic research,

H Lüllmann, and E U Mösinger

Lysosomal enzyme activities in conjunctival tissues of patients with keratoconus.

October 1994, Archives of ophthalmology (Chicago, Ill. : 1960),

H Lüllmann, and E U Mösinger

Retinal lipidosis in albino rats treated with chlorphentermine and with tricyclic antidepressants.

May 1976, Acta neuropathologica,

H Lüllmann, and E U Mösinger

Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.

May 1978, Virchows Archiv. B, Cell pathology,