-transparent.png){kind=logo}
OBJECTIVE To ascertain frequency of inherent mdr-1 gene expression in several common neoplasms. METHODS One hundred fifty one surgically resected tumor specimens confirmed pathologically to be malignant from preoperatively untreated cancer patients were studied. Expression of mdr-1 gene was examined by RT-PCR. RESULTS The frequency of primary mdr-1 gene expression was 33.3% for cancer of the stomach and gastric cardia (17/51), 37% for cancer of the esophagus (17/46), 31.3% for cancer of the colon and rectum (5/16), 13.2% for cancer of the breast (2/15), 40.0% for cancer of the thyroid (4/10), 55.0% for cancer of the lung (5/9) and 0% for cancer of the uterine cervix (0/4). CONCLUSIONS Primary mdr-1 gene expression is relatively of frequent occurrence as detected by RT-PCR technique.
L Yin, and
K Chen, and
D Li
March 2001,
Histopathology,
L Yin, and
K Chen, and
D Li
January 1993,
Cancer chemotherapy and pharmacology,
L Yin, and
K Chen, and
D Li
December 2017,
Scientific reports,
L Yin, and
K Chen, and
D Li
November 1994,
The Prostate,
L Yin, and
K Chen, and
D Li
January 2015,
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer,
L Yin, and
K Chen, and
D Li
May 2006,
Zhonghua zhong liu za zhi [Chinese journal of oncology],
L Yin, and
K Chen, and
D Li
August 2002,
Ai zheng = Aizheng = Chinese journal of cancer,
L Yin, and
K Chen, and
D Li
October 1990,
Gan to kagaku ryoho. Cancer & chemotherapy,
L Yin, and
K Chen, and
D Li
January 2002,
American journal of veterinary research,
L Yin, and
K Chen, and
D Li
November 2018,
Clinical and experimental immunology,
