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Naproxen2, (+)-6-methoxy-alpha-methyl-2-naphthalene acetic acid, is a new non-steroidal anti=inflammatory agent advocated for use in rheumatiod arthritis, degenerative joint disease and ankylosing spondylitis. Published data suggest that in rheumatiod arthritis, naproxen 500mg daily comparable in efficacy with moderate doses of aspirin (3.6 to 4g daily) or 150mg daily of indomethacin, but generally causes fewer and milder side-effects than these drugs at the dosages used and can be given less frequently (12-hourly). Encouraging intial results have been reproted from its use in other inflammatory joint disorders, including acute gout and juvenile rheumatiod arthritis. It has compared favourably with indomethacin in ostioarthrosis of the hip of knee. Its exact place in the management of ankylosing spondylitis remains to be determined.
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
October 1979,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
November 1980,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
April 1980,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
September 1981,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
August 1995,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
December 1978,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
November 1987,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
May 1985,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
August 1983,
Drugs,
R N Brogden, and
R M Pinder, and
P R Sawyer, and
T M Speight, and
G S Avery
February 1979,
Drugs,
