Biomaterial Database

Selective contrast-enhanced MR angiography. 2000

C Bos, and H F Smits, and C J Bakker, and M A Viergever

Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands. clemens@isi.uu.nl

In this study the feasibility of intraarterial contrast administration was investigated. Its use for navigation and treatment evaluation during MR-guided intravascular interventions was explored in phantom and animal experiments. An injection protocol was developed, which accounts for sequence parameters and vessel flow rate. Tracking a bolus of contrast agent was useful to verify the catheter tip position and to assess flow conditions. Compared to intravenous contrast-enhanced magnetic resonance angiography (CE-MRA), selective contrast administration permitted a strongly reduced dose. In two-dimensional (2D) acquisitions overlap of vessels was prevented. Injection and acquisition were easily and accurately synchronized in selective 3D CE-MRA, and a high contrast concentration could be maintained during the entire acquisition. Selective injection is useful in the course of an intervention, to facilitate navigation, provide information on flow conditions, and to evaluate treatment progress repeatedly.

UI	MeSH Term	Description	Entries
D011673	Pulsatile Flow	Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.	Flow, Pulsating,Perfusion, Pulsatile,Flow, Pulsatile,Flows, Pulsatile,Flows, Pulsating,Perfusions, Pulsatile,Pulsatile Flows,Pulsatile Perfusion,Pulsatile Perfusions,Pulsating Flow,Pulsating Flows
D003287	Contrast Media	Substances used to allow enhanced visualization of tissues.	Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D005240	Feasibility Studies	Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.	Feasibility Study,Studies, Feasibility,Study, Feasibility
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013552	Swine	Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).	Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog
D018810	Magnetic Resonance Angiography	Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.	Angiography, Magnetic Resonance,MRI Angiography,Perfusion Magnetic Resonance Imaging,Perfusion Weighted MRI,Angiographies, MRI,Angiographies, Magnetic Resonance,Angiography, MRI,MRI Angiographies,MRI, Perfusion Weighted,Magnetic Resonance Angiographies
D019047	Phantoms, Imaging	Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)	Phantoms, Radiographic,Phantoms, Radiologic,Radiographic Phantoms,Radiologic Phantoms,Phantom, Radiographic,Phantom, Radiologic,Radiographic Phantom,Radiologic Phantom,Imaging Phantom,Imaging Phantoms,Phantom, Imaging
D019786	Gadolinium DTPA	A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)	Gadopentetate Dimeglumine,Gd-DTPA,Gadolinium DTPA Dimeglumine,Gadolinium DTPA Dimeglumine Salt,Gadolinium DTPA Disodium Salt,Gadolinium Diethylenetriaminepenta-acetic Acid,Gadopentetic Acid,Magnevist,Magnevist Enteral,Magnograf,Magnograf Enteral,DTPA, Gadolinium,Diethylenetriaminepenta-acetic Acid, Gadolinium,Dimeglumine, Gadolinium DTPA,Dimeglumine, Gadopentetate,Gadolinium Diethylenetriaminepenta acetic Acid,Gd DTPA