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Forty-two infants, some premature, with enteropathogenic Esch. coli (EPEC) gastroenteritis were treated with an oral suspension of fosfomycin in a dose of 100 and 200 mg/kg per day. After the treatment there were 11 secondary clinical infections (6 reinfections and 5 relapses) which received a second treatment with fosfomycin. In total, 53 treatments were made with fosfomycin and in 92% of the cases there was both clinical and bacteriological cure. 93% of the EPEC strains were sensitive to fosfomycin in vitro, their minimum inhibitory concentrations being less than 64 mug/ml. The concentration of fosfomycin in blood and faeces was assayed by a diffusion plate microbiological method in a group of these children, showing that this antibiotic is partly absorbed and the rest eliminated in the faeces, where its concentration was found to be very high. Tolerance of the product was good, and there were neither toxic nor side effects.
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
January 1977,
Chemotherapy,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
October 1971,
Archives of disease in childhood,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
July 1977,
Indian journal of pediatrics,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
July 1963,
Voprosy okhrany materinstva i detstva,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
January 1959,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
June 1962,
Postgraduate medical journal,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
February 1964,
Clinical pediatrics,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
January 1976,
Ciba Foundation symposium,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
January 1970,
British heart journal,
F Baquero, and
E Canedo, and
A RODRIGUEZ, and
E Jaso
November 2015,
Diagnostic microbiology and infectious disease,
