BIOMAT Database Logo BIOMAT Database Logo

[Lipopolysaccharides of Shigella sonnei]. 2000

E V Borisova, and V A Borisov
T. Shevchenko Kiev University, Ukraine.

Immunobiological properties of native lipopolysaccharides (LPS) from virulent and avirulent strains of Shigella sonnei bacteria (LPS-V and LPS-A, respectively) were studied. In avirulent bacteria, LPS-V induced immunosuppressive activity specific of the virulent strain. LPS of the avirulent strain, whereas LPS-A lacked this property. Native LPS-V with immunosuppressive activity were isolated from the virulent strain by and immune affinity method. Treatment of LPS-V with phenol or TCA abolished its activity and converted it into the LPS-A form. The data showed that LPS-A can be converted back to the LPS-V form by redox treatment. This approach seems to be promising for activating LPS extracted from cells with TCA or a water-phenol mixture.

UI MeSH Term Description Entries
D008070 Lipopolysaccharides Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed) Lipopolysaccharide,Lipoglycans
D004405 Dysentery, Bacillary DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest). Shigellosis,Dysentery, Shiga bacillus,Dysentery, Shigella boydii,Dysentery, Shigella dysenteriae,Dysentery, Shigella dysenteriae type 1,Dysentery, Shigella flexneri,Dysentery, Shigella sonnei,Shigella Dysentery,Shigella Infection,Bacillary Dysentery,Dysenteries, Shigella,Dysenteries, Shigella boydii,Dysenteries, Shigella dysenteriae,Dysenteries, Shigella flexneri,Dysenteries, Shigella sonnei,Dysentery, Shigella,Infection, Shigella,Infections, Shigella,Shiga bacillus Dysentery,Shigella Dysenteries,Shigella Infections,Shigella boydii Dysenteries,Shigella boydii Dysentery,Shigella dysenteriae Dysenteries,Shigella dysenteriae Dysentery,Shigella flexneri Dysenteries,Shigella flexneri Dysentery,Shigella sonnei Dysenteries,Shigella sonnei Dysentery
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000942 Antigens, Bacterial Substances elaborated by bacteria that have antigenic activity. Bacterial Antigen,Bacterial Antigens,Antigen, Bacterial
D012764 Shigella sonnei A lactose-fermenting bacterium causing dysentery. Bacterium sonnei
D014774 Virulence The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS. Pathogenicity

Related Publications

E V Borisova, and V A Borisov
Ultrastructure of lipopolysaccharides from Shigella sonnei.
January 1973, Archivum immunologiae et therapiae experimentalis,
E V Borisova, and V A Borisov
Studies on Shigella sonnei phase I and phase II lipopolysaccharides.
January 1974, Journal of hygiene, epidemiology, microbiology, and immunology,
E V Borisova, and V A Borisov
Immunochemical characteristics of Shigella sonnei and serotype 6 Shigella flexneri lipopolysaccharides and enterobacterial common antigen.
January 1978, Archivum immunologiae et therapiae experimentalis,
E V Borisova, and V A Borisov
Shigella sonnei.
August 2020, Trends in microbiology,
E V Borisova, and V A Borisov
[Shigella sonnei biotypes].
March 1963, Annales de l'Institut Pasteur,
E V Borisova, and V A Borisov
Shigella Sonnei vaccine.
September 1999, Drugs in R&D,
E V Borisova, and V A Borisov
Shigella sonnei meningitis.
January 1996, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
E V Borisova, and V A Borisov
Shigella sonnei myocarditis.
July 1987, Clinical cardiology,
E V Borisova, and V A Borisov
Shigella sonnei bacteremia.
February 1980, Clinical pediatrics,
E V Borisova, and V A Borisov
[Features of the monosaccharide composition and ultrastructure of lipopolysaccharides of different forms of Shigella sonnei].
June 1977, Zhurnal mikrobiologii, epidemiologii i immunobiologii,
Copied contents to your clipboard!