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The agglutinating antibody responses in duodenal fluid and serum were measured serially in 15 infants with enteropathogenic E. coli gastroenteritis. Peak levels of duodenal agglutinins were recorded eight to 18 days after the onset of symptoms, and the titres fell within the next seven to 14 days. These antibodies were mainly of the IgA class but IgM antibodies were detected early in the response, especially in the youngest infants. Serum antibody responses were detected in eight patients, but they correlated poorly with the titres of intestinal antibodies. No rise in serum antibodies was found in six infants. Further studies are required to determine whether these differences are host-derived or whether they reflect different pathogenic properties of the infecting organisms.
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
January 1976,
Ciba Foundation symposium,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
January 1959,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
September 1955,
Acta medica Orientalia,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
February 1954,
Deutsche medizinische Wochenschrift (1946),
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
September 1967,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
June 1958,
Annales de l'Institut Pasteur,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
February 1964,
Clinical pediatrics,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
April 1971,
Cellular immunology,
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
April 1971,
Lancet (London, England),
A S McNeish, and
N Evans, and
H Gaze, and
K B Rogers
November 1956,
Laval medical,
