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Lithium is used with great success in the treatment of manic patients and for prophylaxis of bipolar disorders. There are only few reports about neuropsychiatric side effects at therapeutic serum levels. We report on a 38 year old woman with bipolar disorder who was treated with lithium for 20 years without side-effects. Subsequent to a manic episode, she became disoriented at night and showed marked memory deficits. The patient did not show any neurological or gastrointestinal signs of intoxication. Lithium serum-levels were in therapeutic range. The psychiatric symptoms disappeared when lithium was stopped. We interpret these symptoms as delirant syndrome with pseudo-dementia at therapeutic lithium serum levels. This side-effect must be taken into account even in patients on successful longtime lithium therapy.
R Niethammer, and
A Keller, and
M Weisbrod
November 2000,
Psychiatrische Praxis,
R Niethammer, and
A Keller, and
M Weisbrod
January 2018,
American journal of therapeutics,
R Niethammer, and
A Keller, and
M Weisbrod
July 1997,
Der Nervenarzt,
R Niethammer, and
A Keller, and
M Weisbrod
October 1982,
The American journal of psychiatry,
R Niethammer, and
A Keller, and
M Weisbrod
January 1992,
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R Niethammer, and
A Keller, and
M Weisbrod
May 1990,
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R Niethammer, and
A Keller, and
M Weisbrod
February 1981,
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R Niethammer, and
A Keller, and
M Weisbrod
October 1984,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
R Niethammer, and
A Keller, and
M Weisbrod
July 1985,
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R Niethammer, and
A Keller, and
M Weisbrod
January 1989,
Nederlands tijdschrift voor geneeskunde,
