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MCRs of testosterone (T) and 5 alpha-dihydrotestosterone (DHT) were determined in the morning and evening in four chronically chaired adult rhesus monkeys (Macaca mulatta) by means of steady state infusion of [4-14C]testosterone and [1,2-3H]dihydrotestosterone. Morning and evening MCRs were comparable for both T and DHT, averaging 169 and 212 ml/min for T and 93 and 108 ml/min for DHT, respectively, indicating that temporal differences in blood steroid concentrations are the result of changes in glandular secretion and/or synthesis and not differences in MCRs. Blood transfer factors for the conversion of T to DHT were also similar at these two times (0.024 and 0.022). MCRs were determined in one monkey by the single injection of [14C]T and [3H]DHT. From the rates at which the hormones disappeared from the circulation, MCRT and MCRDHT were calculated to be 172 ml/min for T and 92.2 ml/min for DHT. The inner volumes of hormone distribution were 4.04 liters for T and 3.67 liters for DHT.
S A Sholl, and
P T Toivola, and
J A Robinson
December 1974,
Biology of reproduction,
S A Sholl, and
P T Toivola, and
J A Robinson
February 1978,
Psychosomatic medicine,
S A Sholl, and
P T Toivola, and
J A Robinson
January 1981,
Psychoneuroendocrinology,
S A Sholl, and
P T Toivola, and
J A Robinson
October 1978,
Physiology & behavior,
S A Sholl, and
P T Toivola, and
J A Robinson
October 1985,
Journal of steroid biochemistry,
S A Sholl, and
P T Toivola, and
J A Robinson
October 1974,
Steroids,
S A Sholl, and
P T Toivola, and
J A Robinson
February 1985,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
S A Sholl, and
P T Toivola, and
J A Robinson
August 1978,
Endocrinology,
S A Sholl, and
P T Toivola, and
J A Robinson
June 1982,
Life sciences,
S A Sholl, and
P T Toivola, and
J A Robinson
January 1977,
International journal of fertility,
