-transparent.png){kind=logo}
To establish the relative potency of naproxen and aspirin for oral analgesia, a 4-point, noncrossover bioassay with placebo control was undertaken with 197 patients. Subjective-response methods were used to determine two measures of postoperative analgesia over a period of 6 hr. With reasonable confidence for an oral analgesic assay, we found 220 mg of naproxen to be equivalent to 600 mg of aspirin for pain relief and 330 mg of naproxen to be equivalent to 600 mg of aspirin for decreased pain intensity.
Related Publications
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
April 1978,
Clinical pharmacology and therapeutics,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
April 1974,
Clinical pharmacology and therapeutics,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
November 1982,
Anesthesia progress,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
May 1973,
Lancet (London, England),
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
April 1981,
Journal of clinical pharmacology,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
January 1979,
The Journal of rheumatology,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
April 1977,
Clinical pharmacology and therapeutics,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
January 1980,
The Journal of rheumatology,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
July 1980,
Journal of clinical pharmacology,
D L Mahler, and
W H Forrest, and
C R Brown, and
P F Shroff, and
H E Gordon, and
B W Brown, and
K E James
January 1973,
Scandinavian journal of rheumatology. Supplement,
