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Effect of angiotensin-converting enzyme inhibitor on cardiopulmonary baroreflex sensitivity in patients with acute myocardial infarction. 2000
M Hikosaka, and
F Yuasa, and
R Yuyama, and
M Motohiro, and
J Mimura, and
A Kawamura, and
T Sumimoto, and
T Sugiura, and
T Iwasaka
The Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan.
We evaluated the effect of angiotensin-converting enzyme inhibition (quinapril) on cardiopulmonary baroreflex sensitivity in 30 patients with uncomplicated myocardial infarction (quinapril group, 15 patients; placebo group, 15 patients) at 5 and 10 days after the onset of myocardial infarction. This study indicates that quinapril improved cardiopulmonary baroreflex and thus reduced sympathetic outflow in patients with acute myocardial infarction.
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