Biomaterial Database

Classifying choledochal cysts using hepatobiliary scintigraphy. 2000

A Rajnish, and S Gambhir, and B K Das, and R Saxena

Department of Nuclear Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Utter Pradesh, India.

OBJECTIVE This retrospective study was designed to classify choledochal cysts on the basis of the findings of hepatobiliary scintigraphy. METHODS Twenty-one patients with choledochal cysts (15 female, 6 male; mean age, 20 years) proved on the findings of endoscopic retrograde cholangiopancreatography (ERCP) or surgery and histopathologic analysis were included in the study. Two nuclear medicine physicians, blinded with regard to cholangiographic and operative details, were asked to review and to classify the type of choledochal cyst seen on the hepatobiliary scan. Later, scintigraphic results were compared with ERCP and surgical findings for a reference standard. RESULTS The findings of hepatobiliary scintigraphy correlated with ERCP and surgical findings in 18 of 21 cases (86%). Scintiscans correctly identified all type 1 cysts (12/12). The sensitivity of scintigraphy in diagnosing type 4 cysts was 66% (6 of 9 cases). It underestimated the intrahepatic extent of disease in type 4a biliary cysts (37%). CONCLUSIONS This study illustrates the utility of hepatobiliary scintigraphy in diagnosing type 1 and 4 choledochal cysts.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D002758	Cholangiography	An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.	Cholangiographies
D002760	Cholangiopancreatography, Endoscopic Retrograde	Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.	ERCP,Endoscopic Retrograde Cholangiopancreatography,Retrograde Cholangiopancreatography, Endoscopic,Cholangiopancreatographies, Endoscopic Retrograde,Endoscopic Retrograde Cholangiopancreatographies,Retrograde Cholangiopancreatographies, Endoscopic
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D012680	Sensitivity and Specificity	Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	Specificity,Sensitivity,Specificity and Sensitivity
D015529	Choledochal Cyst	A congenital anatomic malformation of a bile duct, including cystic dilatation of the extrahepatic bile duct or the large intrahepatic bile duct. Classification is based on the site and type of dilatation. Type I is most common.	Choledochal Cyst, Type I,Common Bile Duct Cyst,Congenital Biliary Dilatation,Congenital Choledochal Cyst,Bile Duct Cysts,Choledochal Cyst, Diverticulum,Choledochal Cyst, Type II,Choledochal Cyst, Type III,Choledochal Cyst, Type IV,Choledochal Cyst, Type V,Choledochal Diverticulum,Choledochocele,Cyst, Common Bile Duct,Cysts, Common Bile Duct,Intrahepatic Choledochal Cyst,Multiple Choledochal Cysts,Bile Duct Cyst,Biliary Dilatation, Congenital,Choledochal Cyst, Congenital,Choledochal Cyst, Intrahepatic,Choledochal Cyst, Multiple,Choledochal Cysts,Choledochal Cysts, Diverticulum,Choledochal Diverticulums,Choledochoceles,Congenital Biliary Dilatations,Congenital Choledochal Cysts,Cyst, Bile Duct,Cyst, Choledochal,Cyst, Congenital Choledochal,Cyst, Intrahepatic Choledochal,Cyst, Multiple Choledochal,Dilatation, Congenital Biliary,Diverticulum Choledochal Cyst,Diverticulum Choledochal Cysts,Diverticulum, Choledochal,Duct Cyst, Bile,Intrahepatic Choledochal Cysts,Multiple Choledochal Cyst