[Metastases to the lungs in patients with osteogenic sarcoma--treatment results]. 2000

A Szafrański, and W Woźniak
Klinika Chirurgii Onkologicznej Dzieci, Instytut Matki i Dziecka w Warszawie, ul. Kasprzaka 17a, 01-211 Warszawa, Polska. imid@imid.med.pl

At the National Research Institute of Mother and Child, 158 patients, aged 3 to 21 years were treated for osteosarcoma, in the period 1985 - 1994. Metastases were found in 34 persons. Localisation of metastases: lungs - 32 cases, lungs and additionally bones - 6 cases, CNS - 1 case, bones without pulmonary changes - 2 cases. Chemotheraphy (acc. to different programmes) was the initial treatment. When stabilization or partial regression was observed, operative procedures were undertaken. In the case of progression, conservative treatment was used; changing chemothrapy protocol, or using palliative treatment. Following surgical procedures were made: thoracotomy - 8 cases, sternotomy - 5 cases, excision of bone tumour - 2 cases, laminectomy - 2 cases, excision of CNS tumour - 1 case. In the group of 18 patients where conservative treatment only was used, 2 children are alive. In the group of 16 patients where surgery was performed, 9 are alive. The authors suggest that in case of osteosarcoma it is profitable to extract metastatic foci in the period of stabilization after chemotherapy. It appears important to excise the metastatic foci even 2-3 times as this considerably prolongs survival in these children.

UI MeSH Term Description Entries
D008175 Lung Neoplasms Tumors or cancer of the LUNG. Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D008297 Male Males
D010166 Palliative Care Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed) Palliative Treatment,Palliative Supportive Care,Palliative Surgery,Palliative Therapy,Surgery, Palliative,Therapy, Palliative,Care, Palliative,Palliative Treatments,Supportive Care, Palliative,Treatment, Palliative,Treatments, Palliative
D001859 Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. Bone Cancer,Cancer of Bone,Cancer of the Bone,Neoplasms, Bone,Bone Neoplasm,Neoplasm, Bone
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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