Glomerular lesions of diabetes mellitus in Mystromys albicaudatus. 1975

T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend

The kidneys of 175 nondiabetic and diabetic Mystromys albicaudatus were evaluated histologically by light microscopy. The degree of capillary basement membrane thickening and the predominant glomerular histologic pattern were recorded. Statistical analyses indicated that glomerulosclerosis is associated with diabetes in this species. In addition, a granular capillary basement membrane lesion occurred more frequently in diabetic than in nondiabetic animals.

UI MeSH Term Description Entries
D007678 Kidney Glomerulus A cluster of convoluted capillaries beginning at each nephric tubule in the kidney and held together by connective tissue. Glomerulus, Kidney
D002196 Capillaries The minute vessels that connect arterioles and venules. Capillary Beds,Sinusoidal Beds,Sinusoids,Bed, Sinusoidal,Beds, Sinusoidal,Capillary,Capillary Bed,Sinusoid,Sinusoidal Bed
D002467 Cell Nucleus Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) Cell Nuclei,Nuclei, Cell,Nucleus, Cell
D003928 Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. Diabetic Glomerulosclerosis,Glomerulosclerosis, Diabetic,Diabetic Kidney Disease,Diabetic Nephropathy,Intracapillary Glomerulosclerosis,Kimmelstiel-Wilson Disease,Kimmelstiel-Wilson Syndrome,Nodular Glomerulosclerosis,Diabetic Kidney Diseases,Glomerulosclerosis, Nodular,Kidney Disease, Diabetic,Kidney Diseases, Diabetic,Kimmelstiel Wilson Disease,Kimmelstiel Wilson Syndrome,Nephropathies, Diabetic,Nephropathy, Diabetic,Syndrome, Kimmelstiel-Wilson
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001485 Basement Membrane A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers. Basal Lamina,Basement Lamina,Lamina Densa,Lamina Lucida,Lamina Reticularis,Basement Membranes,Densas, Lamina,Lamina, Basal,Lamina, Basement,Lucida, Lamina,Membrane, Basement,Membranes, Basement,Reticularis, Lamina
D012376 Rodent Diseases Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs). Disease, Rodent,Diseases, Rodent,Rodent Disease
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
May 1970, Archives of pathology,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
February 1972, Archives of pathology,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
November 1974, Diabetologia,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
June 1972, Diabetes,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
October 1987, Laboratory animals,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
April 1975, Laboratory animal science,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
January 1985, Laboratory animals,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
August 1971, Laboratory animal science,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
September 1980, Laboratory investigation; a journal of technical methods and pathology,
T Riley, and R A Stuhlman, and H J Van Peenen, and J A Esterly, and J F Townsend
February 1982, Laboratory animal science,
Copied contents to your clipboard!