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Efficacy of amphotericin B colloidal dispersion in the treatment of Mediterranean visceral leishmaniasis in immunocompetent adult patients. 2000
G B Gaeta, and
A Maisto, and
D Di Caprio, and
A Scalone, and
G Pasquale, and
F M Felaco, and
D Galante, and
L Gradoni
Dipartimento di Malattie Infettive, Seconda Università, Naples, Italy.
Twelve immunocompetent adults with Mediterranean visceral leishmaniasis (VL) were treated with amphotericin B colloidal dispersion (ABCD; 2 mg/kg/d for 7 d). All patients showed rapid clinical response without significant adverse events. Two weeks after therapy they were parasitologically cured and no relapses occurred during 6 months. ABCD is a valid alternative in the management of Mediterranean VL in adult patients.
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