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FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. I. Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation. 2000
Y Nishihara, and
E Tsujii, and
S Takase, and
Y Tsurumi, and
T Kino, and
M Hino, and
M Yamashita, and
S Hashimoto
Fermentation Development Laboratories, Fujisawa Pharmaceutical Co, Ltd, Aichi, Japan.
In the course of our screening for anti-influenza agents of microbial origin, FR191512 was isolated from the cultured broth of fungus strain No. 17415 as colorless powder. The structure of FR191512 was determined by several spectroscopic experiments as a novel polyphenolic compound. This compound showed potent antiviral activity against influenza A virus.
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