BIOMAT Database Logo BIOMAT Database Logo

[Production of superoxide radicals with pulse radiolysis of water with high linear energy transfer]. 2001

G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
DSM/DRECAM/SCM/URA 331 Centre National de la Recherche Scientifique, CEA Saclay, Gif/Yvette, France.

The radiolysis of water with heavy ions of high linear energy transfer (LET) (-dE/dx) is characterized, in deaerated medium, by the production of superoxide anions, the radiolytic yields of which increase with the LET. Radiobiological interest in such radical species comes from the oxidative stress which may be generated by their dismutation in O2 and H2O2 in anoxic medium (radiotherapy with heavy ions). A brief review of the measurements of superoxide free radicals in aqueous solution by indirect or direct methods is presented. Moreover, some experimental results obtained by pulse radiolysis with Ar18+ ions (TEL = 290 keV x microm(-1)), are described. The interpretation of the kinetics takes into account the superoxide absorbance and that of hydrogen peroxide, which is present at the millisecond time scale.

UI MeSH Term Description Entries
D011675 Pulse Radiolysis Use of a pulse of X-rays or fast electrons to generate free radicals for spectroscopic examination. Radiolysis, Pulse
D011868 Radioisotopes Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Daughter Isotope,Daughter Nuclide,Radioactive Isotope,Radioactive Isotopes,Radiogenic Isotope,Radioisotope,Radionuclide,Radionuclides,Daughter Nuclides,Daugter Isotopes,Radiogenic Isotopes,Isotope, Daughter,Isotope, Radioactive,Isotope, Radiogenic,Isotopes, Daugter,Isotopes, Radioactive,Isotopes, Radiogenic,Nuclide, Daughter,Nuclides, Daughter
D004735 Energy Transfer The transfer of energy of a given form among different scales of motion. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed). It includes the transfer of kinetic energy and the transfer of chemical energy. The transfer of chemical energy from one molecule to another depends on proximity of molecules so it is often used as in techniques to measure distance such as the use of FORSTER RESONANCE ENERGY TRANSFER. Transfer, Energy
D006861 Hydrogen Peroxide A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. Hydrogen Peroxide (H2O2),Hydroperoxide,Oxydol,Perhydrol,Superoxol,Peroxide, Hydrogen
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D001128 Argon A noble gas with the atomic symbol Ar, atomic number 18, and atomic weight 39.948. It is used in fluorescent tubes and wherever an inert atmosphere is desired and nitrogen cannot be used. Argon-40,Argon 40
D013481 Superoxides Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. Superoxide Radical,Superoxide,Superoxide Anion
D014867 Water A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Hydrogen Oxide

Related Publications

G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
Effects of linear energy transfer on the radiolysis of water and heavy water.
August 1960, Nature,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
A reinvestigation of the reaction of desferrioxamine with superoxide radicals. A pulse radiolysis study.
January 1990, Free radical research communications,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
On the Primary Water Radicals' Production in the Presence of Gold Nanoparticles: Electron Pulse Radiolysis Study.
December 2020, Nanomaterials (Basel, Switzerland),
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
Radiolysis of confined water: production and reactivity of hydroxyl radicals.
December 2004, Angewandte Chemie (International ed. in English),
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
Pulse radiolysis in study of oxygen radicals.
January 1990, Methods in enzymology,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
A pulse radiolysis study of superoxide dismutase.
May 1972, Biochimica et biophysica acta,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
Pulse radiolysis, free radicals and antiparasitic drugs.
March 1990, Parasitology today (Personal ed.),
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
The production of OH radicals in the radiolysis of water with 4He ions.
May 1989, Radiation research,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
Interaction of radicals from water radiolysis with melanin.
August 1986, Biochimica et biophysica acta,
G Baldacchino, and V Trupin-Wasselin, and S Bouffard, and E Balanzat, and M Gardès-Albert, and Z Abedinzadeh, and D Jore, and S Deycard, and B Hickel
On the spur lifetime and its temperature dependence in the low linear energy transfer radiolysis of water.
December 2012, Physical chemistry chemical physics : PCCP,
Copied contents to your clipboard!