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A method of human venous blood leukocyte culture permits to model immunological processes of an intact organism. Aggregation with lymphoid elements of the central target cell serves as a morphological expression of complicated cell interrelations under conditions of their extracorporeal cultivation. It may be that such interaction of mononuclears in the culture was caused by a special humoral factor generated by lymphocytes. The occurrence of the "rosette" phenomenon in the autoculture permits to suppose that there is a possibility of obtaining an antigenic information by lymphoid elements in the intact organism. The existence of a correlation between the processes of formation of intercellular associations in vitro and the severity of the disease in persons with allergy confirms this supposition.
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
September 1977,
Transplantation,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
November 1975,
Journal of immunology (Baltimore, Md. : 1950),
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1982,
Cellular immunology,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1977,
Monographs in allergy,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1980,
Sovetskaia meditsina,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1979,
Voprosy onkologii,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1976,
Immunological communications,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
September 1974,
Immunology,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
January 1976,
Laboratornoe delo,
V P Lozovoĭ, and
A F Smyshliaeva, and
A A Prikhodchenko, and
N G Odintsova
March 1971,
Clinical and experimental immunology,
