Chromosome heterozygosity and de novo chromosome rearrangements in mammalian interspecies hybrids. 2001

R J O'Neill, and M D Eldridge, and J A Graves
School of Biological Sciences, Division of Environmental and Life Sciences, Macquarie University, Australia. roneill@uconnvm.uconn.edu

UI MeSH Term Description Entries
D007614 Macropodidae A family of herbivorous leaping MAMMALS of Australia, New Guinea, and adjacent islands. Members include kangaroos, wallabies, quokkas, and wallaroos. Kangaroos,Macropus,Petrogale,Quokkas,Setonix,Wallabies,Wallabies, Rock,Wallaroo,Macropus robustus,Kangaroo,Petrogales,Quokka,Rock Wallabies,Rock Wallaby,Wallaby,Wallaby, Rock,Wallaroos
D008322 Mammals Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young. Mammalia,Mammal
D002678 Chimera An individual that contains cell populations derived from different zygotes. Hybrids,Chimeras,Hybrid
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014178 Translocation, Genetic A type of chromosome aberration characterized by CHROMOSOME BREAKAGE and transfer of the broken-off portion to another location, often to a different chromosome. Chromosomal Translocation,Translocation, Chromosomal,Chromosomal Translocations,Genetic Translocation,Genetic Translocations,Translocations, Chromosomal,Translocations, Genetic
D018740 Genetic Heterogeneity The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992) Heterogeneity, Genetic,Genetic Heterogeneities,Heterogeneities, Genetic
D020223 Chromosome Painting A technique for visualizing CHROMOSOME ABERRATIONS using fluorescently labeled DNA probes which are hybridized to chromosomal DNA. Multiple fluorochromes may be attached to the probes. Upon hybridization, this produces a multicolored, or painted, effect with a unique color at each site of hybridization. This technique may also be used to identify cross-species homology by labeling probes from one species for hybridization with chromosomes from another species. Chromosome Paintings,Painting, Chromosome,Paintings, Chromosome

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