Quantitative level of protection offered to workers by ACGIH threshold limit values occupational exposure limits. 2001

M A Jayjock, and P G Lewis, and J R Lynch
Rohm and Haas Co., Spring House, PA, USA.

The details of the example or modeling methodologies used herein are not critical to the general point of this article, which advises the estimation of residual risk at the OEL by using some quantitative modeling structure. Specifically, the authors believe that an explicit attempt to gauge the level of residual risk at the OEL based on conceptual stochastic models with transparent and testable assumptions could be seen as an important enhancement to the process. This is especially true in sharing the OEL deliberations and explaining OEL decisions to the stakeholders. Indeed, if this approach is used, it is critically important to understand and continually communicate that this "cloud of uncertainty" represents model estimates in which the true risk would most likely be less than worst case estimates and could possibly be zero. It is also possible but highly unlikely that it could be higher than the worst case upper-bound estimate. The above quantitative estimation scheme represents a possible improvement that could provide a reasoned attempt on the part of the risk assessors to use rational science (i.e., conceptual models with transparent and testable assumptions) to inform all of the OEL users and stakeholders of their meaning.

UI MeSH Term Description Entries
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000395 Air Pollutants, Occupational Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. Occupational Air Pollutants,Pollutants, Occupational Air
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.
D016272 Occupational Health The promotion and maintenance of physical and mental health in the work environment. Employee Health,Industrial Health,Industrial Hygiene,Occupational Safety,Health, Industrial,Hygiene, Industrial,Safety, Occupational,Health, Employee,Health, Occupational
D016273 Occupational Exposure The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation. Exposure, Occupational,Exposures, Occupational,Occupational Exposures
D018570 Risk Assessment The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988) Assessment, Risk,Benefit-Risk Assessment,Risk Analysis,Risk-Benefit Assessment,Health Risk Assessment,Risks and Benefits,Analysis, Risk,Assessment, Benefit-Risk,Assessment, Health Risk,Assessment, Risk-Benefit,Benefit Risk Assessment,Benefit-Risk Assessments,Benefits and Risks,Health Risk Assessments,Risk Analyses,Risk Assessment, Health,Risk Assessments,Risk Benefit Assessment,Risk-Benefit Assessments
D019055 No-Observed-Adverse-Effect Level The highest dosage administered that does not produce toxic effects. NOAEL,No-Observed-Effect Level,Acceptable Daily Intake,Tolerable Daily Intake,Acceptable Daily Intakes,Daily Intake, Acceptable,Daily Intake, Tolerable,Daily Intakes, Acceptable,Daily Intakes, Tolerable,Intake, Acceptable Daily,Intake, Tolerable Daily,Intakes, Acceptable Daily,Intakes, Tolerable Daily,Level, No-Observed-Adverse-Effect,Level, No-Observed-Effect,Levels, No-Observed-Adverse-Effect,Levels, No-Observed-Effect,No Observed Adverse Effect Level,No Observed Effect Level,No-Observed-Adverse-Effect Levels,No-Observed-Effect Levels,Tolerable Daily Intakes
D020711 Threshold Limit Values Standards for limiting worker exposure to airborne contaminants. They are the maximum concentration in air at which it is believed that a particular substance will not produce adverse health effects with repeated daily exposure. It can be a time-weighted average (TLV-TWA), a short-term value (TLV-STEL), or an instantaneous value (TLV-Ceiling). They are expressed either as parts per million (ppm) or milligram per cubic meter (mg/m3). Short-Term Exposure Limit,STEL,TLV-BLV,TLV-Biological Limit Value,TLV-Ceiling,TLV-STEL,TLV-TWA,TLV-Time Weighted Average,STELs,TLV BLV,TLV Ceiling,TLV STEL,TLV TWA,TLV-BLVs,TLV-Ceilings,TLV-STELs,TLV-TWAs

Related Publications

M A Jayjock, and P G Lewis, and J R Lynch
January 1986, La Medicina del lavoro,
M A Jayjock, and P G Lewis, and J R Lynch
January 1963, Rodo kagaku. The Journal of science of labour,
M A Jayjock, and P G Lewis, and J R Lynch
December 1991, Arhiv za higijenu rada i toksikologiju,
M A Jayjock, and P G Lewis, and J R Lynch
January 1974, Journal of occupational medicine. : official publication of the Industrial Medical Association,
M A Jayjock, and P G Lewis, and J R Lynch
August 2018, Regulatory toxicology and pharmacology : RTP,
M A Jayjock, and P G Lewis, and J R Lynch
June 1971, American Industrial Hygiene Association journal,
M A Jayjock, and P G Lewis, and J R Lynch
May 1993, American journal of industrial medicine,
M A Jayjock, and P G Lewis, and J R Lynch
January 1964, American Industrial Hygiene Association journal,
M A Jayjock, and P G Lewis, and J R Lynch
November 1972, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
Copied contents to your clipboard!