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Computer methods developed by the authors for analysis of fraction labelled mitoses curves (FLM curves) have been compared. Four test examples were used in the study; the first example was the synthesis of a FLM curve with fixed parameters and the others involved fitting actual data. Experimental FLM curves showing various degrees of damping were used in the curve fitting tests. In each test example the comparison was based on the assumptions of exponential growth, a growth fraction of unity and no cell loss. In three of the test examples good agreement between the methods was observed but in one example some important discrepancies arose in the analysis of a heavily damped FLM curve.
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
December 1974,
Tsitologiia,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
September 1973,
Cell and tissue kinetics,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
October 1996,
Cell proliferation,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
March 1973,
Biomedicine / [publiee pour l'A.A.I.C.I.G.],
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
December 1968,
ANL,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
December 1969,
ANL,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
January 1977,
Journal of theoretical biology,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
April 1984,
Journal of pharmacological methods,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
January 1971,
Cell and tissue kinetics,
N R Hartmann, and
C W Gilbert, and
B Jansson, and
P D MacDonald, and
G G Steel, and
A J Valleron
April 1988,
Journal of anatomy,
