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The report summarizes the main results obtained in the course of our research project. The results of immunological and epidemiological studies provide further proofs that human papillomaviruses (HPV) are the etiological agents in cervical neoplasia. In addition, they raise hopes that immunological methods may be utilized in diagnostics of cervical cancer and for monitoring the clinical course of this disease in the near future. Since the etiological relationship between HPV and cervical carcinoma seems to be proven beyond reasonable doubt, the development of prophylactic and therapeutic vaccines has become the dominant of the contemporary HPV reseach. For studying immune reactions against HPV-induced tumours we developed a model of HPV16-transformed rodent cells.
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
May 1988,
Casopis lekaru ceskych,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
October 2003,
Therapeutische Umschau. Revue therapeutique,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
March 2003,
Nihon rinsho. Japanese journal of clinical medicine,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
January 1995,
IARC monographs on the evaluation of carcinogenic risks to humans,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
December 1994,
Infectious disease clinics of North America,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
January 2007,
IARC monographs on the evaluation of carcinogenic risks to humans,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
January 1994,
Annual review of microbiology,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
November 1994,
HNO,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
July 1990,
Human pathology,
V Vonka, and
E Hamsíková, and
E Sobotková, and
M Smahel, and
H Kitasato, and
H Sainerová, and
V Ludvíková, and
R Zák, and
J Kanka, and
Z Kolár, and
J Kovarík
January 1993,
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer,
