Several pre-existing anterior and posterior dental bridge models using Finite elements and the new ceramic material In-Ceram have been developed. The mechanical behaviour of these models has been compared with optimised profiles obtained from a newly developed evolutionary algorithm known as Evolutionary Structural Optimisation (ESO). The results show that the mechanical behaviour of the bridges was mainly restricted by the properties of the porcelain veneer and the design of the bridges themselves. For the case of the anterior bridge, it was found that there existed a specific thickness of veneer that minimised the maximum principal stress. This was related to peak stresses that occurred at the bridge surface. Peak stresses also occurred in the material interface between the In-Ceram and the veneer. These extreme stresses were attributed to the notch size and shape. For the case of the posterior bridge, it was concluded that the shape of the bottom of the Pontic tooth is crucial in reducing the magnitude of the maximum principal tensile stress. The ESO process produced bridge designs which have uniformly stressed bridge surfaces, and which also have significantly lower maximum principal tensile stresses compared to the pre-existing designs (up to 44%).