Computer simulation of non-newtonian effects on blood flow in large arteries. 2001

A Leuprecht, and K Perktold
Institute of Mathematics, Technical University Graz, Graz, Austria.

The influence of viscoelastic effects on blood flow in large arteries is studied numerically. The description of the blood flow uses the conservation of mass and momentum and a constitutive relation of Jeffreys' type (Oldroyd-B) and appropriate relations to describe the shear thinning behaviour. The steady flow studies are carried out in an axisymmetric tube with a local constriction modelling a stenosed blood vessel and in a three-dimensional 90 degrees curved tube. The numerical approach applies a decoupled technique where the computation of kinematics and stresses is separated. The governing equations are solved by means of an upwind stabilised Galerkin finite element method. The numerical results indicate significant influence of viscoelastic effects in the stenosed model. The flow through the curved tube shows minor quantitative viscoelastic influence. The influence of the shear thinning effect can be observed in both geometries. The results demonstrate that the viscoelastic behaviour of the local flow patterns in large arteries is dependent on the shape of the flow domain.

UI MeSH Term Description Entries
D008955 Models, Cardiovascular Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment. Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D001809 Blood Viscosity The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA. Blood Viscosities,Viscosities, Blood,Viscosity, Blood
D003198 Computer Simulation Computer-based representation of physical systems and phenomena such as chemical processes. Computational Modeling,Computational Modelling,Computer Models,In silico Modeling,In silico Models,In silico Simulation,Models, Computer,Computerized Models,Computer Model,Computer Simulations,Computerized Model,In silico Model,Model, Computer,Model, Computerized,Model, In silico,Modeling, Computational,Modeling, In silico,Modelling, Computational,Simulation, Computer,Simulation, In silico,Simulations, Computer
D003251 Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions. Stenosis,Stricture,Constriction, Pathological,Pathologic Constriction,Constrictions, Pathologic,Pathologic Constrictions,Pathological Constriction,Stenoses,Strictures
D004548 Elasticity Resistance and recovery from distortion of shape.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001158 Arteries The vessels carrying blood away from the heart. Artery
D018056 Hemorheology The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS. Hemorrheology

Related Publications

A Leuprecht, and K Perktold
January 1993, Journal of biomechanics,
A Leuprecht, and K Perktold
December 2023, Computer methods and programs in biomedicine,
A Leuprecht, and K Perktold
January 2005, Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference,
A Leuprecht, and K Perktold
September 1999, Medical & biological engineering & computing,
A Leuprecht, and K Perktold
January 2014, Computational and mathematical methods in medicine,
A Leuprecht, and K Perktold
January 2020, Bio-medical materials and engineering,
A Leuprecht, and K Perktold
January 2006, Journal of biomechanics,
A Leuprecht, and K Perktold
June 1991, Australasian physical & engineering sciences in medicine,
A Leuprecht, and K Perktold
January 1994, Biorheology,
Copied contents to your clipboard!