-transparent.png){kind=logo}
Benazepril hydrochloride, a new non-sulfhydryl ACE inhibitor (ACEI) was studied in a titrated dose of 10 mg-20 mg once a day for 6 weeks in 42 mild to moderate adult hypertensive patients with sitting diastolic blood pressure (SDBP) 95-114 mm Hg. The pre-drug SDBP(mean +/- SE) of 102.5 +/- 0.8 mm Hg showed a significant reduction to 87.5 +/- 0.93 mm Hg at the end of treatment. BP was controlled (SDBP < or = 90 mm Hg) in 34 (81%) patients and a drop of at least 10 mm Hg from the pre-treatment SDBP value was noted in 34 (81%) patients. Common adverse reaction was cough in 8(19%) patients. Clinically significant changes in laboratory evaluations were not seen in any patient. Study showed that benazepril in a dose range of 10 to 20 mg per day is an effective agent for treatment of mild to moderate hypertension.
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
April 1993,
ANNA journal,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
March 1991,
Clinical pharmacology and therapeutics,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
June 1995,
Cardiovascular drugs and therapy,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
October 1991,
Cardiologia (Rome, Italy),
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
August 1991,
Clinical cardiology,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
January 1997,
West African journal of medicine,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
February 1999,
The Journal of the Association of Physicians of India,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
July 1997,
Orvosi hetilap,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
March 1987,
The New Zealand medical journal,
N D Karnik, and
Y K Oza, and
S P Sane, and
R Kaushik, and
A D Bhatt, and
K P Chawla, and
A B Vaidya, and
V H Yajnik, and
R C Khokhani
December 1998,
Medizinische Klinik (Munich, Germany : 1983),
