A clinical study was made of three cases of Ameloblastoma (Adamantinoma) of the maxilla. One case presented with oro-antral fistula following extraction of a molar tooth. Extensive bone destruction and involvement of ethmoidal air sinuses and nasal cavity was seen in one of the patients. At times histological diagnosis can be difficult; therefore, accurate diagnosis should be obtained by an experienced histopathologist. Partial maxillectomy with a wide margin of healthy bone should be the choice of treatment in the majority of cases. There tumours are sensitive to deep-X-ray to a varying degree. One should consider radiotherapy post-operatively if growth has been excised inadequately. Radiotherapy may be helpful when surgery is contraindicated.