The cineangiographically determined left ventricular function was studied in normals and in CAD-patients with one- and three-vessel disease. From single plane RAO-LV-cineangiograms following parameters were calculated; LV-volumes (EDV, ESV) according to the area-length method, ejection fraction (EF), percentage shortening of the medial perpendicular short axis delta (M,deltaMpl), mean velocity of circumferential fiber shortening (V(CF), V(CFPL)). It can be concluded that there is 1. no correlation between the severity of coronary heart disease and the morphological left ventricular wall lesions, 2. a depressed left ventricular function in coronary heart disease and normal ventriculograms, 3. a more impaired left ventricular function when cineangiograms show hypokinesis or aneurysms, 4. hypokinesis or aneurysms in the anterior wall leads to a more depressed left ventricular function than the same lesions in the posterior wall.