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[The combined procedure of limbal transplantation (LT) and penetrating keratoplasty (PK) for severe ocular obsolete chemical or thermal burns]. 1997

X Gong, and H Liu, and X Zhong, and L Chen
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.

OBJECTIVE To improve the prognosis of grafts for obsolete ocular chemical or thermal burns. METHODS LT + PK or PK were performed in 28 eyes with severe chemical or thermal burns. The effects of the two groups were compared. RESULTS In LT + PK group(12 eyes), during 5 to 28 months of follow-up, the results showed improved visual acuity in 9 eyes (75%), maintained stable epithelial adhesion without recurrent erosion or persistent epithelial defect in 11 eyes (91.67%), graft transparent in 9 eyes (75%). Nine eyes (75%) showed prevented neovascularization and conjunctival tissue from growing into graft. Allograft rejection were identified in 4 eyes (33.33%). In routine PK group (16 eyes), during 3 to 22 months of follow-up, the results showed improved visual acuity in 4 eyes (25%), maintained stable epithelial adhesion without recurrent erosion or PCED in 8 eyes (50%), graft transparent in 4 eyes (25%). Four eyes (25%) showed prevented neovascularization and conjunctival tissue from growing into cornea. CONCLUSIONS Combined procedure of LT and PK is an effective treatment for severe ocular chemical or thermal burns. It can reduce persistent corneal epithelial defect and prevent neovascularization and conjunctival epithelial from growing into cornea thus maintaining graft transparent and improving visual acuity.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002057 Burns, Chemical Burns caused by contact with or exposure to CAUSTICS or strong ACIDS. Chemical Burns,Burn, Chemical,Chemical Burn
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005126 Eye Burns Injury to any part of the eye by extreme heat, chemical agents, or ultraviolet radiation. Burn, Eye,Burns, Eye,Eye Burn
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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