[Determination of antimicrobial preservative dimethyl fumarate by high performance liquid chromatography]. 1998

S Liu, and K Su
College of Chemistry and Chemical Engineering, Ocean University of Qingdao, Qingdao, 266003.

This paper described a HPLC method for determining dimethyl fumarate (DMF), a new antimicrobial preservative. Chromatographic conditions were as follows: Micropak MGH 5 mu cap column, 4.00 mm x 300.0 mm EtOH-H2O (90:10, V/V) eluent, and UV detector at 216 nm. In the range of 0.036-2.96 micrograms, the sample size and peak area showed a linear relationship with regression equation, Y = 3.215 x 10(-6)X - 0.04797 and r = 0.9996. Standard deviation was 3.2 x 10(-4).

UI MeSH Term Description Entries
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D005650 Fumarates Compounds based on fumaric acid. Fumarate,Fumaric Acid Ester,Fumaric Acid Esters,Fumarate Esters,Acid Ester, Fumaric,Acid Esters, Fumaric,Ester, Fumaric Acid,Esters, Fumarate,Esters, Fumaric Acid
D005659 Fungicides, Industrial Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. Industrial Fungicides
D000069462 Dimethyl Fumarate A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS. 2-butenedioic acid, (2E)-, dimethyl ester,BG 00012,BG 12 compound,BG-00012,BG-12 compound,BG00012,BG12 compound,Dimethylfumarate,FAG 201,FAG-201,FAG201,Fumaderm,Tecfidera,00012, BG,12 compound, BG,201, FAG,Fumarate, Dimethyl,compound, BG 12,compound, BG12

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