-transparent.png){kind=logo}
Linkage mapping of a nonspecific form of X-linked mental retardation (MRX53) in a large Pakistani family. 2001
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
Telethon Institute of Genetics and Medicine, Milan, Italy.
Nonspecific X-linked mental retardation is a nonprogressive, genetically heterogeneous condition that affects cognitive function in the absence of other distinctive clinical manifestations. We report here linkage data on a large Pakistani family affected by a form of X-linked nonspecific mental retardation. X chromosome genotyping of family members and linkage analysis allowed the identification of a new disease locus, MRX53. The defined critical region spans approximately 15 cM between DXS1210 and DXS1047 in Xq22.2-26. A LOD score value of 3.34 at no recombination was obtained with markers DXS1072 and DXS8081.
Related Publications
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
January 1991,
American journal of medical genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
April 1999,
American journal of medical genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
November 1992,
Human genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
January 1992,
American journal of medical genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
June 1993,
American journal of human genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
February 1976,
Clinical genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
July 1996,
American journal of medical genetics,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
January 1999,
European journal of human genetics : EJHG,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
January 2009,
Medycyna wieku rozwojowego,
W Ahmad, and
S Noci, and
M Faiyaz ul Haque, and
T Sarno, and
P Aridon, and
M M Ahmad, and
M Amin-Ud-Din, and
M A Rafiq, and
S ul Haque, and
M De Fusco, and
A Ballabio, and
B Franco, and
G Casari
January 1982,
Human genetics,
