Treatment of keloid scars with pulsed dye laser and intralesional steroid. 2000

P G Connell, and C C Harland
Laser Unit, Sutton Hospital, Epsom and St Helier NHS Trust, Cotswold Road, Sutton, Surrey, SM2 5NF, UK.

OBJECTIVE Keloid scars have been treated in many ways, with varying success. A wide variety of treatments, all in current usage, indicate that no treatment has been shown to be markedly superior to the others. Following the successful treatment of scars using the pulsed dye laser, and with the more traditional intralesional steroid injection, a pilot study was undertaken using a combination of these treatments. METHODS Recalcitrant keloid scars of 10 patients were managed with a combined treatment modality of pulsed dye laser (PDL) and intralesional steroid. RESULTS Seven of the patients benefited in terms of the raised nature of the scars being improved by 60%, erythema improved by 40%, and pain/itching by 75%. Three of the patients, who had presternal scars, had no benefit. CONCLUSIONS Pretreatment with PDL facilitated steroid injection by making the scar oedematous and therefore softer. In addition, we speculate that the benefits of this combined modality are summative, not just adjunctive. This study demonstrates that this treatment is effective for the treatment of keloid scars when other treatments have been unsuccessful.

UI MeSH Term Description Entries
D007627 Keloid A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues. Keloids
D008297 Male Males
D008775 Methylprednisolone A PREDNISOLONE derivative with similar anti-inflammatory action. 6-Methylprednisolone,Medrol,Metipred,Urbason,6 Methylprednisolone
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077555 Methylprednisolone Acetate Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY. Acetyl-Methylprednisolone,Depo-Medrol,Depo-Medrone,Methylprednisolone Acetate, (11beta,16alpha)-isomer,Methylprednisolone Acetate, (11beta,16beta)-isomer,Methylprednisolone-21-acetate,Acetyl Methylprednisolone,Depo Medrol,Depo Medrone,Methylprednisolone 21 acetate
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

P G Connell, and C C Harland
May 1995, Lancet (London, England),
P G Connell, and C C Harland
November 2012, Expert review of medical devices,
P G Connell, and C C Harland
November 1998, Plastic and reconstructive surgery,
P G Connell, and C C Harland
July 2006, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.],
P G Connell, and C C Harland
August 2016, Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology,
P G Connell, and C C Harland
June 2013, The British journal of dermatology,
P G Connell, and C C Harland
December 2006, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
P G Connell, and C C Harland
February 2017, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.],
Copied contents to your clipboard!