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In our attempts at establishing a cancer cell line from various ascites of cancer bearing patients, a cell line was successfully established from the ascites of a 63-year-old female with primary ovarian tumor (embryonal carcinoma). Histological findings of the peritoneum, due to metastasis, appeared to be cystadenocarcinoma, revealing the differentiation to non-epithelial cells which formed coarse networks and fibers, and morphologic changes of tissue cultures also reflected such histologic findings. At present the subculture has reached the 95th population doubling level, and cultured cells have assumed the morphology of mesothelial cells or fibroblasts with about 50 chromosomes. As a human malignant cell line, it is useful for the study of human malignant tumor cell.
T Kimoto, and
A Ueki, and
K Nishitani
March 1983,
Cancer research,
T Kimoto, and
A Ueki, and
K Nishitani
February 1978,
Gan,
T Kimoto, and
A Ueki, and
K Nishitani
May 1980,
Acta pathologica et microbiologica Scandinavica. Section A, Pathology,
T Kimoto, and
A Ueki, and
K Nishitani
January 1990,
Nihon Sanka Fujinka Gakkai zasshi,
T Kimoto, and
A Ueki, and
K Nishitani
September 1992,
The Biochemical journal,
T Kimoto, and
A Ueki, and
K Nishitani
November 1979,
Cancer research,
T Kimoto, and
A Ueki, and
K Nishitani
September 1982,
In vitro,
T Kimoto, and
A Ueki, and
K Nishitani
January 2001,
International journal of urology : official journal of the Japanese Urological Association,
T Kimoto, and
A Ueki, and
K Nishitani
January 1987,
Hepatology (Baltimore, Md.),
T Kimoto, and
A Ueki, and
K Nishitani
February 1989,
British journal of cancer,
