-transparent.png){kind=logo}
We assessed the effectiveness of end-to-side nerve coaptation by evaluating the extent of reinnervation and the integrity of the donor nerve in the rat. Fifty-six Sprague-Dawley rats were randomly divided into "fresh" and "predegenerated" (delayed) repair groups with or without a window in the perineurium. The right peroneal nerve was cut and sutured to the tibial nerve in an end-to-side fashion. Two and 3 months postoperatively, we measured the nerve conduction velocity (NCV) of the peroneal and tibial nerves, took dry muscle weights, and performed histologic studies. Peroneal NCV recovered up to 71% (2 mo) and 79% (3 mo), and tibial NCV recovered up to 88% (2 mo) and 91% (3 mo). The latter results indicate that this procedure had a slightly negative effect on donor tibial NCV. Dry weight of the tibialis anterior muscle returned to 60% (2 mo) and 82% (3 mo) of that of the contralateral side. Histologic results showed that there were numerous regenerating axons in the distal end of the peroneal nerve. Presence of a window in the perineurium improved the histologic profile significantly.
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
July 1999,
British journal of plastic surgery,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
January 2002,
The Journal of hand surgery,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
November 2008,
Hand clinics,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
February 2007,
Experimental neurology,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
March 2010,
Neurosurgery,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
September 2005,
Annals of plastic surgery,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
May 2007,
Journal of neurotrauma,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
January 2007,
Journal of plastic, reconstructive & aesthetic surgery : JPRAS,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
July 2003,
Journal of reconstructive microsurgery,
Z Zhang, and
P N Soucacos, and
J Bo, and
A E Beris, and
K N Malizos, and
E Ioachim, and
N J Agnantis
March 2008,
Neurosurgery,
