| D007559 |
Ivermectin |
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form. |
Eqvalan,Ivomec,MK-933,Mectizan,Stromectol,MK 933,MK933 |
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| D008800 |
Mexico |
A country in NORTH AMERICA, bordering the Caribbean Sea and the Gulf of Mexico, between BELIZE and the UNITED STATES, and bordering the North Pacific Ocean, between Guatemala and the UNITED STATES. |
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| D009855 |
Onchocerciasis |
Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions. |
Onchocerciases |
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| D002489 |
Central America |
A region of southern NORTH AMERICA extending from the southern border of MEXICO to the northern border of COLOMBIA. It separates the Caribbean Sea from the Pacific Ocean and is linked to SOUTH AMERICA by the Isthmus of Panama. |
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| D003140 |
Communicable Disease Control |
Programs of surveillance designed to prevent the transmission of disease by any means from person to person or from animal to man. |
Flatten the Curve of Epidemic,Flattening the Curve, Communicable Disease Control,Parasite Control,Control, Communicable Disease,Control, Parasite |
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| D005369 |
Filaricides |
Pharmacological agents destructive to nematodes in the superfamily Filarioidea. |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D013020 |
South America |
The southern continent of the Western Hemisphere, extending southward from the Colombia-Panama border. |
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