-transparent.png){kind=logo}
1. Hypoxic and hypercapnic ventilatory drives were measured in eight healthy male subjects before and after ingestion of ethanol, in a dose of 17 mmol/kg body weight. 2. A significant decrease in hypoxic ventilatory drive was observed at 20 min after ethanol (P less than 0.05). A significant depression in hypercapnic drive was observed at 70 min after indigestion of ethanol (P less than 0.05). The mean peak blood ethanol (24mmol/1) occurred at 20 min, at which time the lowest mean hypoxic drive was recorded. 3. Ethanol in moderate doses produced a depression of both hypoxic and hypercapnic ventilatory drives in normal subjects. This suggests that ethanol may play a role in the precipitation of acute respiratory failure in certain patients in whom the ventilatory drive is already impaired, as in chronic airways obstruction.
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
September 1990,
The Journal of physiology,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
May 1997,
Respiration physiology,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
August 1987,
Clinical science (London, England : 1979),
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
January 1964,
Quarterly journal of experimental physiology and cognate medical sciences,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
September 1959,
Journal of applied physiology,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
January 1963,
Clinical pharmacology and therapeutics,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
October 1962,
The Yale journal of biology and medicine,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
June 1989,
British journal of anaesthesia,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
January 1978,
Journal of psychosomatic research,
S A Sahn, and
S Lakshminarayan, and
D J Pierson, and
J V Weil
October 1974,
Clinical science and molecular medicine,
