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1. Simultaneous platelet and fibrinogen survival studies were carried out on a group of seven normal persons and eleven diabetic patients. 2. Survival time was calculated: (a) by measuring the interval between 50% of the maximum radioactivity in the anabolic phase and 50% of the maximum radioactivity in the catabolic phase, and (b) by fitting an exponential function to the decay phase of the curve. 3. With the first method, the normal group had a mean plaetelet survival which did not differ significantly from that in the diabetic group. With the second method, however, the platelet half-life in the diabetic patients was significantly shorter than in the normal subjects. 4. Fibrinogen survival was significantly shorter in the diabetic group with either method. 5. It is concluded that there is an increased utilization of platelets and fibrinogen in diabetic subjects.
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
April 1974,
British journal of haematology,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
June 1975,
Thrombosis et diathesis haemorrhagica,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
April 1968,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
March 1970,
British journal of haematology,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
December 1969,
British medical journal,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
December 1966,
Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
May 1971,
British journal of haematology,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
January 1978,
Acta medica Academiae Scientiarum Hungaricae,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
November 1975,
The British journal of nutrition,
J C Ferguson, and
N Mackay, and
J A Philip, and
D J Sumner
July 1973,
The British journal of nutrition,
