In vascular surgery department of V. Vakhidov Research Center of Surgery 37 patients with diffuse lesion of popliteal-tibial arterial segment in combination with stenotic lesion of profound and common femoral artery were examined and operated. Examination of regional circulation before operation was made with consideration of profundo-popliteal collateral index (PPCI) which permits to evaluate features and degree of lesion of deep femoral artery (DFA). Angiography failed to defect bifurcation of the femoral artery in 17 (48.6%) cases, in 11 of them stenosis of bifurcation of the femoral artery was revealed in intraoperative revision. In these patients PPCI was 0.34 and more, high peripheral vascular resistance was seen in debitometry. The authors believe that calculation of PPCI is one of the main methods of diagnosis of femoral artery bifurcation lesions. Good and satisfactory results were seen in 29 (78.3%) patients, unsatisfactory--in 8. Amputations were performed in 3 patients. 1 patient died. Suppuration of the wounds was in 6 patients, in 4 of them--in the zone of reconstructed artery with arrhosive bleeding. It is suggested that in diffuse lesions of arteries of popliteal-tibial segment examinations of regional hemodynamics and plastic repair of DFA are most effective.