Biomaterial Database

X-ray diffraction study on interdigitated structure of phosphatidylcholines in glycerol. 2001

H Takahashi, and N Ohta, and I Hatta

Department of Physics, Gunma University, 4-2 Aramaki, Maebashi 371-8510, Japan. htakahas@fs.aramaki.gunma-u.ac.jp

X-ray diffraction was used to study the interdigitated structure of phosphatidylcholines (PCs) in glycerol. In this study, we investigated five different saturated diacyl PCs with carbon number from 14 to 18 in their acyl chains. It was found that lamellar spacings increase linearly as increasing the carbon number in the chains and that the increment is 0.10+/-0.01 nm per one carbon atom. The lamellar diffraction intensity data were analyzed, by applying a method proposed by Adachi [Chem. Phys. Lipids 107 (2000) 93]. The results indicate that the moiety around polar headgroup regions is almost unchanged, being independent of the carbon number.

UI	MeSH Term	Description	Entries
D010713	Phosphatidylcholines	Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	Choline Phosphoglycerides,Choline Glycerophospholipids,Phosphatidyl Choline,Phosphatidyl Cholines,Phosphatidylcholine,Choline, Phosphatidyl,Cholines, Phosphatidyl,Glycerophospholipids, Choline,Phosphoglycerides, Choline
D005990	Glycerol	A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent.	1,2,3-Propanetriol,Glycerin,1,2,3-Trihydroxypropane,Glycerine
D013329	Structure-Activity Relationship	The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.	Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D014961	X-Ray Diffraction	The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Xray Diffraction,Diffraction, X-Ray,Diffraction, Xray,Diffractions, X-Ray,Diffractions, Xray,X Ray Diffraction,X-Ray Diffractions,Xray Diffractions