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High serum interleukin-10 and tumor necrosis factor alpha levels in chronic paracoccidioidomycosis. 2001
M C Fornari, and
A J Bava, and
M T Guereño, and
V E Berardi, and
M R Silaf, and
R Negroni, and
R A Diez
Laboratorio de Inmunofarmacologia, Facultad de Medicina (UBA), Paraguay 2155, Piso 16, 1121 Buenos Aires, Argentina.
In patients with chronic paracoccidioidomycosis (n = 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean +/- standard error of the mean), were higher than in normal controls (n = 8): 186 +/- 40 versus 40 +/- 7 (P < 0.05), 203 +/- 95 versus 20 +/- 8 (P = 0.001), and 96.3 +/- 78.57 versus 1.19 +/- 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.
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