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We studied the impact of acute 10-min normobaric hypoxia on myocardial electrical stability, systolic and diastolic cardiac functions in 10 young healthy men. Hypoxia induced a decrease of ejection fraction and left ventricular early peak filling velocity. The QTc interval was prolonged during normobaric hypoxia without QT dispersion increase. Electrocardiographic investigation with assessment of QT-interval must be mandatory before normobaric hypoxic therapy is started. Prolonged QT interval is contraindication to normobaric hypoxic therapy.
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