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A wide variety of organisms (the so-called "anhydrobiotes') is able to survive long periods of time in a state of utmost dehydration and can thus survive in extremely dry environments including artificially imposed or space vacuum. Known strategies of survival include the accumulation of certain polyols, especially disaccharides, which help prevent damage to membranes and proteins. Here we report that DNA in vacuum-dried spores is damaged to a very substantial degree by processes leading to DNA strand breaks. Most of these lesions are obviously repaired during germination, but extensive damage to DNA and enzymes after long exposure times (months to years) finally diminish the chances of survival.
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
June 2020,
Nature methods,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
January 2004,
DNA repair,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
May 1979,
Biochemical pharmacology,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
March 2021,
Molecular cell,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
July 1999,
Genetika,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
January 2024,
Trends in biochemical sciences,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
October 1976,
Virology,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
January 1977,
Biochimica et biophysica acta,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
December 1985,
Biochemical and biophysical research communications,
K Dose, and
A Bieger-Dose, and
M Labusch, and
M Gill
November 1975,
Radiation research,
