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A 25-year old Caucasian with uniquely severe and chronic periodontal disease, requiring extraction of all teeth, was treated with hexahydrocoenzyme Q4 which functions like naturally occurring coenzyme Q10 in gingival tissue. During the fourth and fifth examinations after the seventh and eighth weeks of treatment, three dentists separately and independently scored clinical improvements of five symptoms by significances of essentially P less than 0.01 to P less than 0.001. The initial benefit of the treatment was observed at the second examination after three weeks of treatment. The administration of coenzyme Q could be an important therapeutic adjunct to periodontal therapy for certain patients.
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
January 1973,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
January 1967,
Journal of dental research,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
April 1973,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
January 2010,
Developmental disabilities research reviews,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
June 1999,
RN,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
October 1971,
Proceedings of the National Academy of Sciences of the United States of America,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
September 1995,
British dental journal,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
March 1998,
The Journal of the Association of Physicians of India,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
August 2016,
Biochimica et biophysica acta,
Y Iwamoto, and
R Nakamura, and
K Folkers, and
R F Morrison
March 1965,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
