An ex vivo investigation into the fluoride release and absorption profiles of three orthodontic adhesives. 2001

A K Coonar, and S P Jones, and G J Pearson
Department of Orthodontics, Eastman Dental Institute for Oral Health Care Sciences, University College London, UK.

Prevention of peri-bracket decalcification is essentially mediated by effective oral hygiene, which is patient dependent. The potential to compensate for poor oral hygiene may be through the release of free fluoride ions from direct bonding agents. It is well established that glass ionomer cements (GICs) release free fluoride ions which may be replenished by exposure to fluoride containing solutions. The aim of this ex vivo study was to compare the fluoride release and absorption profiles of a recently developed low fusion, monophase GIC, Limerick glass, with two materials in common clinical use, namely, Fuji-Ortho L.C. and Concise. Ten test specimens of each material were fabricated and stored in deionized water at 37 degrees C. The concentration of fluoride release was measured daily for the first 7 days after immersion and then weekly for 5 weeks. On day 42 the test specimens were recharged in 2 per cent sodium fluoride solution and fluoride release was measured initially after 24 hours and then every 48 hours. The recharge regimen was repeated for 3 weeks. Both Limerick glass and Fuji-Ortho L.C. demonstrated the characteristic fluoride release pattern of GIC with a rapid elution of fluoride after the first 24 hours followed by a more gradual release profile over the following 2 weeks. Fuji-Ortho L.C. released the greatest quantity of fluoride but the release profile of Limerick glass was more sustained. Concise released negligible amounts of fluoride. Limerick glass and Fuji-Ortho L.C. showed an increase (P < 0.01) in fluoride release following exposure to 2 per cent sodium fluoride that decreased both with time and subsequent exposures to fluoride supplement.

UI MeSH Term Description Entries
D007101 Immersion The placing of a body or a part thereof into a liquid. Submersion,Immersions,Submersions
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D002327 Cariostatic Agents Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) Cariostatic Effect,Cariostatic Effects,Agent, Cariostatic,Agents, Cariostatic,Cariostatic Agent,Effect, Cariostatic,Effects, Cariostatic
D003738 Dental Cements Substances used to bond COMPOSITE RESINS to DENTAL ENAMEL and DENTIN. These bonding or luting agents are used in restorative dentistry, ROOT CANAL THERAPY; PROSTHODONTICS; and ORTHODONTICS. Dental Adhesives,Luting Agents,Orthodontic Adhesives,Cement, Dental,Cements, Dental,Dental Cement,Adhesive, Dental,Adhesive, Orthodontic,Adhesives, Dental,Adhesives, Orthodontic,Dental Adhesive,Luting Agent,Orthodontic Adhesive
D004058 Diffusion The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT. Diffusions
D005459 Fluorides Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. Fluoride
D005899 Glass Ionomer Cements A polymer obtained by reacting polyacrylic acid with a special anion-leachable glass (alumino-silicate). The resulting cement is more durable and tougher than others in that the materials comprising the polymer backbone do not leach out. Glass Ionomer Cement,Glass Polyalkenoate Cement,Polyalkenoate Cement,Polyalkenoate Cements,Glass Polyalkenoate Cements,Glass-Ionomer Cement,Cement, Glass Ionomer,Cement, Glass Polyalkenoate,Cement, Glass-Ionomer,Cement, Polyalkenoate,Cements, Glass Ionomer,Cements, Glass Polyalkenoate,Cements, Glass-Ionomer,Cements, Polyalkenoate,Glass-Ionomer Cements,Ionomer Cement, Glass,Polyalkenoate Cement, Glass
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000042 Absorption The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
D000180 Acrylic Resins Polymers of high molecular weight which are derived from acrylic acid, methacrylic acid or other related compounds and are capable of being molded and then hardened to form useful components. Acrylic Resin,Resin, Acrylic,Resins, Acrylic

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